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Investigation of robustness and dynamic behaviour of G1/S checkpoint/DNA-damage signal transduction pathway based on mathematical modelling and a novel neural network approach
(Lincoln University, 2011)
The control of cell cycle checkpoints in cell cycle regulation is an extremely important function in living organisms. Mutation of the checkpoint regulators can cause gene or chromosome instability, which eventually results ...
Holistic complex systems modelling approaches for cell signalling networks – Mammalian cell cycle control system : A thesis submitted in partial fulfilment of the requirements for the degree of Doctor of Philosophy at Lincoln University
(Lincoln University, 2019)
Cell cycle is a precisely regulated process in which cells of living organisms go through a sophisticated growth and division cycle that eventually leads to production of two daughter cells (Morgan, 2007; Satyanarayana & ...